With the NRL Telstra Premiership back on after a one-week hiatus for a representative weekend, NRL.com has taken a look at how all 16 teams may line up when the competition resumes on Thursday.
The Warriors will be without Euan Aitken and Josh Curran after they were forced to isolate as they were on a flight attended by a cabin crew member who subsequently tested positive to COVID-19.
Mid-season recruits Chad Townsend and Dallin Watene-Zelezniak are likely to be rushed straight into the Warriors' squad to face St George Illawarra in Gosford on Friday night.
The Broncos are set for more changes including in the halves, with Brodie Croft set to earn a recall alongside Tyson Gamble and Corey Oates also returning to first grade.
Penrith will be sweating on star halfback Nathan Cleary, who looked to pick up a shoulder injury in the Blues' State of Origin II win on Sunday night.
Canterbury could be without five players after they breached biosecurity protocols by attending a pub in Sydney's east.
NRL Round 16 predicted team lists
Roosters v Storm, Thursday 7.50pm at McDonald Jones Stadium
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Roosters
1. James Tedesco
2. Daniel Tupou
3. Josh Morris
4. Joseph Manu
5. Matt Ikuvalu
6. Lachlan Lam
7. Sam Walker
8. Jared Waerea-Hargreaves
9. Adam Keighran
10. Siosiua Taukeiaho
11. Angus Crichton
12. Sitili Tupouniua
13. Isaac Liu
14. Samuel Verrills
15. Fletcher Baker
16. Egan Butcher
17. Daniel Suluka Fifita
Sam Walker will likely return in the halves after two weeks to rest his shoulder issues, with Joey Manu returning to the centres bumping out Joseph Suaalii.
Sitili Tupouniua (foot) is likely to be available with one of the younger forwards set to drop out. James Tedesco and Angus Crichton both appeared to come through Origin without issue.
Storm
1. Nicho Hynes
2. George Jennings
3. Reimis Smith
4. Justin Olam
5. Josh Addo-Carr
6. Cameron Munster
7. Jahrome Hughes
8. Tui Kamikamica
9. Brandon Smith
10. Jesse Bromwich
11. Felise Kaufusi
12. Chris Lewis
13. Dale Finucane
14. Aaron Booth
15. Christian Welch
16. Trent Loiero
17. Aaron Pene
Nelson Asofa-Solomona (suspension), Harry Grant (hamstring) and Tom Eisenhuth (elbow) will be missing from the previous game but Brandon Smith (calf) should be OK and Reimis Smith (ankle) is also a strong chance.
Jesse Bromwich (elbow) is likely to return. Ryan Papenhuyzen is targeting a round 20 return. Cameron Munster, Felise Kaufusi and Christian Welch goth through Origin II on Sunday and are set to playl.
Warriors v Dragons, Friday 6pm at Central Coast Stadium
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Warriors
1. Reece Walsh/Roger Tuivasa-Sheck
2. Marcelo Montoya
3. Adam Pompey
4. Rocco Berry
5. Roger Tuivasa-Sheck/Dallin Watene-Zelezniak
6. Kodi Nikorima
7. Chad Townsend
8. Addin Fonua-Blake
9. Wayde Egan
10. Ben Murdoch-Masila
11. Bayley Sironen
12. Eliesa Katoa
13. Tohu Harris
14. Jazz Tevaga
15. Leeson Ah Mau
16. Jack Murchie
17. Kane Evans
Euan Aitken and Josh Curran are set to miss the next two rounds after being on a flight from the Gold Coast to Sydney in which a cabin crew member has since tested positive to COVID-19.
Warriors coach Nathan Brown is likely rush mid-season recruits Chad Townsend and Dallin Watene-Zelezniak straight into the side rather than giving them extra prep time with the team.
Wayde Egan is likely to return from a head knock in place of round-15 debutant Taniela Otukolo while Reece Walsh is under a cloud after a low-grade hamstring strain robbed him of his Origin debut on Sunday.
Dragons
1. Matt Dufty
2. Cody Ramsey
3. Zac Lomax
4. Gerard Beale
5. Jordan Pereira
6. Corey Norman
7. Ben Hunt
8. Blake Lawrie
9. Andrew McCullough
10. Paul Vaughan
11. Tariq Sims
12. Jack Bird
13. Jack de Belin
14. Brayden Wiliame
15. Joshua Kerr
16. Daniel Alvaro
17. Josh McGuire
An interesting team sheet looms at the Dragons, with Matt Dufty (shoulder), Zac Lomax (thumb), Max Feagai (head knock) plus Josh McGuire and Tyrell Fuimaono (suspension) all set to be available.
Mikaele Ravalawa has been suspended for the next four matches. Tariq Sims, Ben Hunt and Andrew McCullough came through Origin II without incident.
Panthers v Eels, Friday 7.55pm at BlueBet Stadium
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Panthers
1. Dylan Edwards
2. Charlie Staines
3. Stephen Crichton
4. Matt Burton/Paul Momirovski
5. Brian To'o
6. Jarome Luai
7. Nathan Cleary/Matt Burton
8. Moses Leota
9. Apisai Koroisau
10. James Fisher-Harris
11. Viliame Kikau
12. Kurt Capewell
13. Isaah Yeo
14. Tyrone May
15. Scott Sorensen
16. Matt Eisenhuth
17. Liam Martin
Nathan Cleary (shoulder) is in some doubt with Paul Momirovski to play centre and Matt Burton halfback if Cleary is ruled out. Viliame Kikau could be back from a minor hamstring strain while the rest of the six-man Origin contingent all came through Sunday night unscathed.
Eels
1. Clint Gutherson
2. Maika Sivo
3. Tom Opacic
4. Waqa Blake
5. Haze Dunster
6. Dylan Brown
7. Mitchell Moses
8. Reagan Campbell-Gillard
9. Joey Lussick
10. Junior Paulo
11. Isaiah Papali'i
12. Ryan Matterson
13. Nathan Brown
14. Will Smith
15. Shaun Lane
16. Marata Niukore
17. Bryce Cartwright
Maika Sivo will return from suspension, meaning two-try debutant Sean Russell will likely make way. Reed Mahoney (shoulder) is unlikely to be back before the round 17 bye, though Nate Roache (knee) will be unavailable meaning Will Smith likely returns. Junior Paulo is set to back up from Origin II.
Bulldogs v Manly, Saturday 3pm at Bankwest Stadium
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Bulldogs
1. Nick Meaney
2. Nick Cotric
3. Will Hopoate
4. Corey Allan
5. Tuipulotu Katoa
6. Brandon Wakeham
7. Jake Averillo
8. Jack Hetherington
9. Jeremy Marshall-King
10. Luke Thompson
11. Corey Waddell
12. Matt Doorey
13. Josh Jackson
14. Sione Katoa
15. Dylan Napa
16. Ava Seumanufagai
17. Ofahiki Ogden
Adam Elliott and Chris Smith have both been ruled out for around six weeks. Corey Allan (shoulder) returned via reserve grade last round.
Dylan Napa, Brandon Wakeham, Aaron Schoupp, Corey Waddell and Sione Katoa's immediate futures are under a cloud after they breached biosecurity protocols by visiting a pub in Eastern Sydney on the weekend.
If all are ruled out the club's depth would be sorely tested with Kyle Flanagan or Lachlan Lewis plus Jackson Topine, Brad Deitz, Joe Stimson and Dean Britt among those likely to be called upon.
Manly
1. Tom Trbojevic
2. Jason Saab
3. Bradley Parker
4. Morgan Harper
5. Reuben Garrick
6. Kieran Foran
7. Daly Cherry-Evans
8. Taniela Paseka
9. Lachlan Croker
10. Martin Taupau
11. Haumole Olakauatu
12. Josh Schuster
13. Jake Trbojevic
14. Dylan Walker
15. Karl Lawton
16. Sean Keppie
17. Toafofoa Sipley
Jake Trbojevic (hip) and Josh Schuster (calf) should be available while Tom Trbojevic was hobbling at times in Origin II and may not be risked, although Daly Cherry-Evans is set to back up. Moses Suli would return to the starting side with Reuben Garrick at fullback if Trbojevic was rested. Curtis Sironen (knee) is getting close to a return.
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Raiders v Titans, Saturday 5.30pm at GIO Stadium
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Raiders
1. Bailey Simonsson
2. Semi Valemei
3. Sebastian Kris
4. Matthew Timoko
5. Jordan Rapana
6. Jack Wighton
7. Samuel Williams
8. Josh Papalii
9. Josh Hodgson
10. Dunamis Lui
11. Corey Harawira-Naera
12. Elliott Whitehead
13. Ryan Sutton
14. Tom Starling
15. Emre Guler
16. Iosia Soliola
17. Joseph Tapine
No major ins or outs expected from round 15, with Josh Papalii and Jack Wighton set to back up from Origin II.
Titans
1. AJ Brimson
2. Greg Marzhew
3. Brian Kelly
4. Patrick Herbert
5. Phillip Sami
6. Ashley Taylor
7. Jamal Fogarty
8. Jarrod Wallace
9. Erin Clark
10. Tino Fa'asuamaleaui
11. Kevin Proctor
12. David Fifita
13. Tyrone Peachey
14. Moeaki Fotuaika
15. Jaimin Jolliffe
16. Samuel McIntyre
17. Mitchell Rein
AJ Brimson (knee) is a chance of returning to displace the impressive Jayden Campbell while Corey Thompson (ankle) may be available. Kevin Proctor returns from a one-game suspension. David Fifita, Tino Fa'asuamaleaui and Moeaki Fotuaika are set to back up from Origin II.
Knights v Cowboys, Saturday 7.30pm at McDonald Jones Stadium
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Knights
1. Kalyn Ponga
2. Dominic Young
3. Brodie Jones
4. Enari Tuala
5. Hymel Hunt
6. Jake Clifford
7. Mitchell Pearce
8. Jacob Saifiti
9. Jayden Brailey
10. Daniel Saifiti
11. Lachlan Fitzgibbon
12. Mitch Barnett
13. Sauaso Sue
14. Connor Watson
15. David Klemmer
16. Jack Johns
17. Josh King
Knights coach Adam O'Brien expects Kalyn Ponga (groin) to make his long-awaited return, while Kurt Mann (ankle) is no certainty.
Brodie Jones may get another game at centre after his match-winning try last start with Mann and Bradman Best injured. Daniel Saifiti should back up from Origin.
Cowboys
1. Valentine Holmes
2. Kyle Feldt
3. Javid Bowen
4. Hamiso Tabuai-Fidow
5. Murray Taulagi
6. Scott Drinkwater
7. Thomas Dearden
8. Coen Hess
9. Reece Robson
10. Jordan McLean
11. Shane Wright
12. Mitchell Dunn
13. Jason Taumalolo
14. Jake Granville
15. Thomas Gilbert
16. Lachlan Burr
17. Francis Molo
No major changes expected from round 15. Maroons trio Val Holmes, Kyle Feldt and Francis Molo should be fine after getting through Origin II on Sunday.
Broncos v Sharks, Sunday 2pm at Suncorp Stadium
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Broncos
1. Tesi Niu
2. Xavier Coates
3. Herbert Farnworth
4. Kotoni Staggs
5. Corey Oates
6. Brodie Croft
7. Tyson Gamble
8. Matthew Lodge
9. Jake Turpin
10. Payne Haas
11. Alex Glenn
12. Keenan Palasia
13. Teui Robati
14. Kobe Hetherington
15. Ethan Bullemor
16. Cory Paix
17. Tom Flegler
Kotoni Staggs is available for the first time this year. Tevita Pangai jnr has been suspended and John Asiata has undergone neck surgery. Albert Kelly (hamstring) is unlikely to return. Early mail out of Red Hill suggests Brodie Croft could replace Karmichael Hunt and Corey Oates is set for a recall in place of Selwyn Cobbo.
Sharks
1. Will Kennedy
2. Connor Tracey
3. Will Chambers
4. Jesse Ramien
5. Ronaldo Mulitalo
6. Matt Moylan
7. Shaun Johnson
8. Aiden Tolman
9. Blayke Brailey
10. Aaron Woods
11. Briton Nikora
12. Siosifa Talakai
13. Toby Rudolf
14. Braydon Trindall
15. Teig Wilton
16. Jack Williams
17. Braden Hamlin-Uele
With no forced changes and no Origin representatives, the Sharks could well be unchanged from round 15.
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Wests Tigers v Rabbitohs, Sunday 4.05pm at Leichhardt Oval
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Wests Tigers
1. Daine Laurie
2. David Nofoaluma
3. Adam Doueihi
4. James Roberts
5. Ken Maumalo
6. Moses Mbye
7. Luke Brooks
8. James Tamou
9. Jacob Liddle
10. Alex Twal
11. Luke Garner
12. Luciano Leilua
13. Joe Ofahengaue
14. Stefano Utoikamanu
15. Michael Chee Kam
16. Tom Amone
17. Alex Seyfarth
Adam Doueihi (head knock) is set to return while Shawn Blore (ankle) is unlikely to be available. It remains to be seen which players, if any, pay the price for last round's capitulation to Melbourne.
Rabbitohs
1. Latrell Mitchell
2. Alex Johnston
3. Dane Gagai
4. Campbell Graham
5. Taane Milne
6. Cody Walker
7. Adam Reynolds
8. Mark Nicholls
9. Damien Cook
10. Tevita Tatola
11. Keaon Koloamatangi
12. Jai Arrow
13. Cameron Murray
14. Benji Marshall
15. Hame Sele
16. Tom Burgess
17. Jacob Host
Benji Marshall (birth of child) will return with Blake Taaffe set to make way. The club's five Origin players got through Sunday night without injury although some could yet be rested.