Adelaide Oval will kick off the 2020 State of Origin series with Sydney hosting the second game on a Sunday and Suncorp Stadium the venue for the finale.
ARL Commission chairman Peter Beattie and South Australian premier Steven Marshall announced the Adelaide match in the South Australian capital on Monday.
Following on from the success of Perth's Optus Stadium hosting Origin II this year, Beattie believes the June 3 fixture at Adelaide will be another high point on the NRL calendar in 2020.
Game two of the series will be in Sydney on June 21 before the final match is played in Brisbane on July 8.
"State of Origin has been an enormous success in Melbourne and Perth in recent years, and we have no doubt that the opening game of the series next year at Adelaide Oval will be an incredible spectacle," Beattie said.
"Origin is a wonderful showpiece for the game and this will allow us to share it with an important new market, bringing new fans closer to the game.
"The support of the South Australian Government, as well as the South Australian Tourism Commission, has been fantastic through the process and we all look forward to returning in June next year for what will be an incredible series opener.
"This year's series provided us some wonderful entertainment and no doubt next year's will bring more brilliant feats and incredible storylines."
Mr Marshall said hosting the match was "a major coup for Adelaide and South Australia".
"This is a fantastic opportunity for our state, not only is it expected to generate an economic benefit of over $15 million, but it will showcase our vibrant city to a huge, national and international TV audience. We look forward to welcoming a sell-out crowd of thousands of visitors to the State of Origin on 3 June 2020."
Individual tickets for the series will go on sale next year but supporters can register their interest for the 2020 Holden State of Origin series at nrl.com/waitlist.
Fans can purchase special NRL Travel packages for Game 1 in Adelaide now, which feature tickets to Game 1, exclusive experiences including a winery tour with Origin legends and a tour of Adelaide Oval via nrltravel.com.