Wests Tigers fullback James Tedesco will miss his side's Round 16 meeting with the Gold Coast Titans at Campbelltown Stadium, cut from the 21-man squad 24 hours prior to kick-off.
The custodian picked up an ankle injury in the NSW Blues' loss to the Queensland Maroons in State of Origin II, and it's yet to be determined at this stage whether he'll be fit to face the Knights in Round 17.
Tedesco also spent some time off the field on Wednesday night due to a HIA but the No.1 later rejoined the action, finishing the match.
Kevin Naiqama will replace Tedesco at fullback, with Malakai Watene-Zelezniak joining the 17 on the wing. Joel Edwards has also been dropped from the squad named on Tuesday.
Captain Aaron Woods will be given up until kick-off to prove his fitness but at this stage should be fine to play.
For the Titans, Chris McQueen has been ruled out with a neck injury. Joe Greenwood will start in his place with Pat Vaivai joining the bench. Origin reps Jarryd Hayne, Nathan Peats and Jarrod Wallace are all still part of the squad with Phillip Sami dropping out.
Wests Tigers
5 Kevin Naiqama
2 David Nofoaluma
3 Esan Marsters
4 Moses Suli
18 Malakai Watene-Zelezniak
6 Tuimoala Lolohea
7 Luke Brooks
8 Aaron Woods (C)
9 Jacob Liddle
10 Ava Seumanufagai
11 Sauaso Sue
12 Kyle Lovett
13 Elijah Taylor
Interchange:
14 Matt Eisenhuth
15 Jacob Junior Felise
16 Michael Chee Kam
17 Matt Mcilwrick
Reserves:
19 Jack Littlejohn
21 Alex Twal
Titans
1 Jarryd Hayne
2 Anthony Don
3 Dale Copley
4 Konrad Hurrell
5 William Zillman
6 Tyrone Roberts
7 Ashley Taylor
8 Jarrod Wallace
9 Nathan Peats
10 Ryan James (C)
11 Kevin Proctor
17 Joe Greenwood
13 Max King
Interchange:
14 John Olive
15 Pat Politoni
16 Morgan Boyle
18 Paterika Vaivai
Reserves:
19 Nathaniel Peteru
20 Agnatius Paasi
21 Jamal Fogarty