Penrith second-row forward Bryce Cartwright has been promoted to the starting side for the clash with Parramatta at ANZ Stadium on Saturday, with James Fisher-Harris succumbing to injury.

Fisher-Harris was named in the Panthers' 17 on Tuesday but had been nursing a shoulder injury, with Cartwright to take his place as he returns from an ankle injury.

Panthers

1. Matt Moylan (C)
2. Waqa Blake
3. Dean Whare
4. Tyrone Peachey
5. Dallin Watene-Zelezniak
6. Te Maire Martin
7. Nathan Cleary
8. James Tamou
9. Peter Wallace
10. Reagan Campbell-Gillard
21. Bryce Cartwright
12. Isaah Yeo
13. Trent Merrin
Interchange:
14. Peta Hiku
15. Leilani Latu
16. Tim Browne
17. Moses Leota
Reserves:
18. Corey Harawira-Naera
19. Sitaleki Akauola